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Isocitrate dehydrogenase involves in oxidative decarboxylation of isocitrate to -ketoglutarate (Figure 4b)

Mercury released into the atmosphere ultimately deposits into aquatic environments or terrestrial surfaces, where it may be transported into water bodies (67)

Beginners should focus on understanding what it does, starting with safe dosages, and combining it with a balanced diet and consistent exercise routine .

Meanwhile, previous studies have reported that NO can disrupt autophagy by the SNO of different proteins, including the components of the mTOR signaling pathway [284]

Therefore, the present review explores the functional mechanisms of mitochondria in ferroptosis and discusses therapeutic strategies targeting mitochondria-mediated ferroptosis for IDD treatment, aiming to provide novel insights for clinical intervention

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