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Consequently, the aforementioned data suggest that particular pathways may have both local and systemic relevance

Yu Y, Huang D, Zhang, Lin, Chen X, Wang Y, Zhang, Lu, Ren M, Liang H

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The effect of silver oxidation on the photocatalytic activity of Ag/ZnO hybrid plasmonic/metal-oxide nanostructures under visible light and in the dark

10.1111/acel.12747 Aging Cell 6 BhuiyanM
So, one could hypothesize that it would contribute to tolerance by diminishing the quantity of available receptor
