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Within the mitochondrial matrix, CPTII catalyzes the re-formation of acyl-CoA from acylcarnitine

[DOI] [PMC free article] [PubMed] [Google Scholar] 43.Holtkamp N., Malzer E., Zietsch J., Okuducu A.F., Mucha J., Mawrin C., Mautner V.F., Schildhaus H.U., von Deimling A

Moreover, L-Carnitine supplementation has been shown to increase protein synthesis in muscle fiber and increased plasma levels of L-leucine, an essential amino acid for protein synthesis [16]

2017, p

In this context, lysine acetylation of CAC prevents carnitine entry into the mitochondria, thus having a detrimental impact on FAO [86]
