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Glutamate is strongly implicated in chemotherapy neurotoxicity (Carozzi et al, 2009) and compounds that inhibit glutamate production have been shown to reduce neuronal damage (particularly in the dorsal root ganglia ) in rat models (Carozzi et al)

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Benlian P, De Gennes JL, Foubert L, Zhang H, Gagne SE, Hayden M

Action and function of Faecalibacterium prausnitzii in health and disease

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Common symptoms include fatigue, cold intolerance, constipation, dry skin, weight gain, depression, and poor concentration