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The FOXO4p53 axis in senescence p53 is a major tumour suppressor and master regulator of cellular stress responses: DNA damage, oxidative stress, oncogene activation

The key functional variant, a short/long repeat polymorphism (5-HTTLPR), influences the expression level of the transporter

To conclude, food consumption, in terms of dietary patterns, rather than dietary glycine intake, is a key determinant of glycine availability, potentially through modulation of glycine endogenous metabolic pathways

These neuroprotective effects are attributed to vitamin Ds ability to influence the production and release of neurotrophins, support neurotransmitter synthesis, maintain intracellular calcium homeostasis, and prevent oxidative damage to nervous tissue (53)

pmid:22909029 15

doi: 10.1152/jappl.1993.75.2.566