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Full story: To view or add a comment, sign in I am excited to share our new study, recently published in MedComm: Loss of Beta-cell Identity and Function as a Mechanism of Secondary Failure of Sulfonylurea Therapy in Diabetes DOI: 10.1002/mco2.70588 Sulfonylureas remain widely prescribed for the treatment of Type 2 Diabetes, yet their effectiveness often declines over time

In a group of PMDS, Jekic et al

NAD+ supplements are marketed for energy support, leading some to consider them as a complementary intervention

TFEB-dependent lysosome biogenesis is required for senescence

Reuhl K

When activated, the mast cells in the skin release mediators (histamines, tryptase, TNF-alpha, CXCL9, etc.) that cause inflammation, flushing, itching, or burning.[ref] Related article: Rosacea, underlying causes, genetic susceptibility Dermatographism and mast cell activation syndrome: In a survey of mast cell activation syndrome, dermatographism was found in 89% of the patients.[ref] Dermatographism is when you get welts or raised red lines when you scratch your skin lightly