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Free Radic Biol Med 40:138145 Saxena VP, Wetlaufer DB (1970) Formation of three-dimensional structure in proteins

Studies have demonstrated that in PCa cell models, treatment with mannan induces significant alterations in mitochondrial structure and a pronounced decrease in mitochondrial membrane potential, indicating mitochondrial dysfunction

Catalase and SOD activities were also found to be significantly elevated in the sera of patients with SLE in another study

[1] Links with fatty acid oxidation Acetyl-CoA and NADH are also produced by fatty acid oxidation , which, like the reactions of the pyruvate dehydrogenase complex, takes place within the mitochondrion