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The studys goal was to find an easy, accurate, and selective way to measure APAP, N-acetyl para benzoquinone imine (NAPQI) (an APAP metabolite that is harmful), and N-acetyl-l-cysteine (NAC) (an antidote)

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Once depleted, cells lose their ability to neutralize reactive oxygen species, defend against ferroptosis, support proper iron metabolism, and maintain immune and neurological function

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All subjects also had a positive [18F]FDG PET/CT scan within 1month prior to the [18F]FSPG PET scan