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Description
MOTS-c's AMPK activation is documented in Cell Metabolism

A 2008 study published in the Journal of Medicinal Chemistry demonstrated metabolic effects in rodent models at 50mg/kg, which led early researchers to extrapolate human-equivalent doses between 50100mg daily

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This may result in a shortage, producing a variety of health concerns such as fatigue, weakness, constipation, loss of appetite, and nerve-related issues

Horm Res 2000
