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We then performed a gene set enrichment analysis (GSEA) to determine the association between the expression of ACTL6A and signaling pathways in the RNA array results, which indicated significant differences between ACTL6A-KD cells and control cells in multiple metabolism-related pathways, among which GSH metabolism ranked as one of the most highly correlated pathways (Fig

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An enzyme called glutathione peroxidase then sparks the conversion of reduced glutathione to oxidized glutathione, a free radical itself

Nencini C, Giorgi G, Micheli L

References Jackson DA, Symons RH, Berg P: Biochemical method for inserting new genetic information into DNA of simian virus 40: circular SV40 DNA molecules containing lambda phage genes and the galactose operon of Escherichia coli