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*Correspondence: Kristine Salma-Ancane, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Pharmacological inhibition of poly(ADP-ribose) polymerases improves fitness and mitochondrial function in skeletal muscle

Bohlender 2005)

Conversely, phenelzine showed no significant benefits [186]

The molecule has been studied in animal models of adipose-tissue metabolism, with published preclinical work examining its effects on NAD+ pool dynamics and on the methyl-donor balance NNMT regulates