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Weeks 5-16: The ramp-up to efficacy During this phase, the dose is gradually increased every few weeks

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Numerous patients exhibit a deficiency in vitamin B12 due to factors such as stress, poor dietary habits, subpar digestion, or the depletion of this crucial nutrient by certain medications

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As genotoxic treatment is clinically very effective but also toxic, we tested whether DPI could reduce the dosage of vincristine required for efficient cancer cell killing