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Anti-HIV effects of IFN/ are mediated by both inhibition of viral assembly and budding [136, 137]
Nonetheless, several positive trends in endpoints were observed in the treated group, [103] leading to wonder how to improve targeting of this agent to the most suitable SLE patients
This seeming discrepancy could be due to differences in measurement methods (e.g., MR sequences and quantification methods) and sampled brain regions, thus warrants further investigation
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In addition, chloroquine has been described to compete with NADH for binding to glycolytic enzyme lactate dehydrogenase, occupying the NADH-binding pocket of this enzyme, which was illustrated in the malarial parasite Plasmodium falciparum [101]
[DOI] [PubMed] [Google Scholar] 280.Inzinger M, Massone C, Arzberger E, Hofmann-Wellenhof R
