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For instance, membrane binding studies propose that a minute number of these PD mutants strongly bind to synthetic membrane vesicles, while others show a weakened ability to bind to the membrane [21]

This is due to a significant decrease in MTHFR enzymatic activity, particularly in the presence of C677T (Ala222Val) and A1298C (Glu429Ala) SNPs

2012;94(Suppl 1):3944
Robayo-Torres, C
