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Modulates cell proliferation and apoptosis (important in cancer and aging)

Comparison of three synthetic transferrin mimetic small peptides to promote the blood-brain barrier penetration of vincristine liposomes for improved glioma targeted therapy

10.1016/j.celrep.2023.112945 226 YangJ.JiangL.MaH.ZhuY.ZhaoX.YangT.et al (2025a)

To comprehensively understand the gene expression changes responsible for the differences in dTTP and GSH biosynthesis, we performed RNA sequencing analysis of WT- and T315I-Bcr-Abl-32D cells

In the context of ARDS, ferroptosis contributes to the destruction of alveolar and endothelial cells, leading to increased vascular permeability, pulmonary edema, and impaired gas exchange