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Most of the time, however, the diagnosis is made late or the disease tends to progress due to its nature

In the course of HIE, a number of mitochondrial functions may be impaired, including inhibition of the respiratory chain, increased production of reactive oxygen species (ROS), loss of mitochondrial membrane potential, or activation of apoptotic pathways

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Its lack primarily affects the nervous system, leading to coordination disorders, and then to the reduction of our ability to recognize