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It is also interesting to note that in the LA group, in contrast to the CE group, we did not find significant associations of the total level of glutathione with cysteine and homocysteine, which may also indicate that this subtype of stroke is more commonly associated with systemic disruption of aminothiols metabolism
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In these patients, mixed agonist/antagonist and partial agonist analgesics may reduce the analgesic effect and/or precipitate withdrawal symptoms [see PRECAUTIONS;Drug Interactions]
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These variations make it challenging to predict disease course and may lead to delayed recognition of symptom significance (Vercellini et al., 2014)

doi: 10.1111/exd.12183 34 ChenXShiCHeMXiongSXiaX
