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Berberine (5001500 mg/day) has shown significant reductions in fasting glucose, post-prandial glucose, and HbA1c in multiple small RCTs and meta-analyses in some studies, outcomes were comparable to metformin, especially in prediabetes and insulin resistance

The global incidence rate has reached 25-35%, with a prevalence of 29.2% in China (13)

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Inactivation of beef brain alpha-ketoglutarate dehydrogenase complex by valproic acid and valproic acid metabolites

ROS-responsive drug delivery system with enhanced anti-angiogenic and anti-inflammatory properties for neovascular age-related macular degeneration therapy