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Heal or Harm: Body Protective Compound-157 in the Gray Zone Ron Panarotti Key Takeaways Human evidence is minimal, limited to 3 uncontrolled pilot studies (n=30), with no validated pharmacokinetics, receptor identification, or long-term safety data to support broad clinical use

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5-amino-1MQ acts as an inhibitor of an enzyme called NNMT that degrades a nicotinamide adenine dinucleotide (NAD+) precursor called nicotinamide, which is also a precursor of nicotinamide mononucleotide (NMN)

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The collagen fibers that give tendons their strength become less organized and more prone to fraying

Fibroblasts are the primary repair cells in tendon tissue