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On the other hand, in the last decades a novel clinically entity has been defined in patients without CD complaining extraintestinal and gastrointestinal symptoms referring to a clear benefit by avoiding gluten from their diet and/or symptom worsening upon gluten reintroduction, namely NCGS (141)

doi: 10.1046/j.1365-2710.1999.00238.x

DeSantis, A

Specifically, MGV enhances the phosphorylation level of AMPK and inhibits the phosphorylation of PI3K and Akt proteins, thereby inhibiting the downstream mTOR signaling pathway

Plant Growth Regul 61:195204 Wang Z, Xiao Y, Chen W, Tang K, Zhang L (2010b) Increased vitamin C content accompanied by an enhanced recycling pathway confers oxidative stress tolerance in Arabidopsis

Furthermore, the protein degradation regulatory system is finely controlled by redox signals, thereby managing the degradation and recycling of damaged or misfolded proteins within cells