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For example, nanocurcumin encapsulated in PLGA shows improved cellular uptake and antitumor effects

however, the opposite situation occurs with GCL

Chronic Stress: High and prolonged stress levels can produce an excess of cortisol and other stress hormones that create oxidative byproducts

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Although it is mainly produced by the liver, virtually every tissue is able to secrete IGF-I for autocrine/paracrine purposes [18]

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