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Notably, inhibition of GLUT1 has been shown to reduce mTOR signalling and attenuate SASP responses, indicating a potential therapeutic strategy for restoring metabolic homeostasis in senescent macrophages [71]

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The PRKN -linked, autosomal-recessive variant of PD (ARPD) is characterized by the selective degeneration of dopamine and noradrenaline producing neurons in the S
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