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Importantly, overexpression of keap1a or knockdown of hmox1a partially rescued the blood clot formation, suggesting that the disrupted Keap1-Nrf2 signaling is responsible for the venous thrombosis-like phenotypes in smarca5 mutants
Glutathione plays a crucial role in detoxification and immune function
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Glutathione is a thiol-containing tripeptide which is considered as a master antioxidant
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