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Treatment with alprazolam was statistically significantly superior to placebo treatment, as measured by the following psychometric instruments: Hamilton Anxiety Rating Scale, Physicians Global Impressions, Target Symptoms, Patients Global Impressions and Self-Rating Symptom Scale

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5.1 Metabolic auxotrophy as an attenuation strategy Metabolic auxotrophy is a classic attenuation approach in which one or more critical genes in vital metabolite biosynthetic pathways are deleted, thereby causing the bacterial cell to rely on an exogenous supply of the targeted metabolite

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Arch Virol 152:747762 Zechmann B, Mauch F, Sticher L, Mller M (2008) Subcellular immunocytochemical analysis detects the highest concentrations of glutathione in mitochondria and not in plastids

Sulforaphane, a Natural Isothiocyanate Compound, Improves Cardiac Function and Remodeling by Inhibiting Oxidative Stress and Inflammation in a Rabbit Model of Chronic Heart Failure