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Description
Genetic or pharmacological inactivation of ABCC1 potentiated the anti-leukemic effects of BH3 mimetic drugs
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Future research, driven by advanced models, biomarker development, and clinical trials, will pave the way for innovative treatments that balance modulation of angiogenesis with preservation of neuronal homeostasis
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Key pathways include PI3K/Akt and MAPK, which promote fibroblast proliferation, collagen synthesis, and angiogenesis
doi: 10.1016/j.neubiorev.2011.05.014
