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The availability of epinephrine nasal spray may reduce barriers to rapid treatment of anaphylaxis. Neffys approval is based on four studies in 175 healthy adults, without anaphylaxis, that measured epinephrine concentrations in the blood following administration of the nasal spray or approved epinephrine injection products

Coull, J

Although there has been great progress in HD pathogenesis, currently available neuroprotective treatment strategies are still insufficient

Mitochondrial calcium uniporter blocker prevents cardiac mitochondrial dysfunction induced by iron overload in thalassemic mice

Its own activity is sensitive to the cell's NAD+ and metabolic state

These changes may impair nutrient absorption and promote hepatic inflammation via the gutliver axis (85, 86)