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Oxidative stress is considered a hallmark of injury of SCI

This finding could lead to a better understanding of the pharmacological uniqueness of clozapine, potential development of a biomarker for treatment resistant schizophrenia and the development of more targeted treatments leading to personalisation of treatment.

all hematologic parameters should be normal before beginning the cyanocobalamin intranasal formulations

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Finally, we show that our model can reveal differences in the processes leading to altered activation dynamics amongst DILI inducing drugs.