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These factors contribute to mitochondrial dysfunction and cognitive impairment in affected individuals ( 5.3 Manifestations of neuropsychiatric system injury Ketamine abuse commonly manifests as dissociative symptoms, such as altered consciousness, detachment from the environment, and sensory loss ( 5.4 Auxiliary examination Neuroimaging studies have provided critical insights into ketamine-induced neurotoxicity

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Characterization of a mammalian homolog of the GCN2 eukaryotic initiation factor 2alpha kinase