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The PNMT encoded enzyme is also involved in the synthesis of several of the trace amine neurotransmitters

Like all medical treatments, B12 injections may cause mild side effects in some individuals

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This hyperpolarization leads to inhibition in the post-synaptic cell, reducing activity, which explains how ACh causes the heart rate to decrease

doi: 10.1172/JCI8124 41 SoumelisVRechePAKanzlerHYuanWEdwardGHomeyBet al

Sanders SP, Zweier JL, Harrison SJ, Trush MA, Rembish SJ, Liu MC: Spontaneous oxygen radical production at sites of antigen challenge in allergic subjects
