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Vigh JP, Kincses A, Ozgr B, Walter FR, Santa-Maria AR, Valkai S, et al
Inhibitors of FAK that target the ATP-binding pocket of the kinase domain have been largely unsuccessful 10,11 , displaying micromolar anti-proliferative effects and no apoptotic effects in cancer cells despite reported nanomolar biochemical potencies for the FAK enzyme 12,13

More Effects of oxidative stress on ASMase activity and LR rearrangement

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In a rat full-thickness wound model, topical or intraperitoneal Thymosin Beta-4 increased reepithelialisation by 42% over saline controls at day 4 and up to 61% by day 7, with wounds contracting at least 11% more than controls (Malinda et al
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