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Experimental models of traumatic brain injury: Do we really need to build a better mousetrap

Liver tissues from hepatocyte-specific Gpx4 -KO mice exhibited robust oxidation of various phospholipids, including PE and PE-p, which carry various PUFA chains 27

During subsequent fetal development, BCAAs can also promote protein synthesis or stimulate the hepatic secretion of hormones such as insulin-like growth factor-I (IGF-I) and IGF-II through the mTOR pathway, thereby supporting fetal growth 320,321,322 (Fig

Chartier-Harlin MC, Kachergus J, Roumier C, Mouroux V, Douay X, Lincoln S, Levecque C, Larvor L, Andrieux J, Hulihan M, et al
While NADPH is essential to regenerate most key antioxidant molecules, it also plays an important role in generating ROS through the action of NADPH oxidases (NOX)

Anyone with uncontrolled diabetes needs to monitor blood glucose very closely given the competing effects of GLP-1 agonism (glucose lowering) and growth hormone (potential glucose raising)
