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Authors' contributions Melissa de Almeida Corra Alfredo: Design and planning of the study, drafting and editing of the manuscript, and approval of the final version of the manuscript

doi: 10.1038/s41598-020-62755-9 67 KostrzewaR

Dosing & Reconstitution Guide Each peptide reconstituted in its own vial CJC-1295 DAC dosed in mg, Ipamorelin in mcg CJC-1295 DAC (5 mg Vial): Standard / Gradual Approach (2 mL = 2.5 mg/mL) Reconstitute: Add 2.0 mL bacteriostatic water to one 5 mg vial final concentration 2.5 mg/mL

Haidar, Tjoson Tjoa The Laryngoscope.2023

Example Dosage Calculation: Animal Model: A standard 30-gram lab mouse

alteplase) at a standard dose of 0.9 mg per kilogram not exceeding 90 mg