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In vitro , drug tolerance and dependence can be studied, as there are molecular markers showing these effects

AP, action potential

studied the effect of pricking and cupping on the abdominal center for biceps after stroke and showed that combined therapy of pricking and cupping along with conventional stroke rehabilitation could contribute significantly to the improvement in hand function and reducing spasticity in stroke patients [223]

Shi et al., 2000)

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Glutathione transferase omega 1 catalyzes the reduction of S-(phenacyl)glutathiones to acetophenones