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Targeting neuroinflammation with pharmacological agents is a promising strategy to reduce the systemic inflammatory response, preserve BBB integrity, and prevent cognitive decline (Fu et al., 2018)

Olokizumab, a monoclonal antibody against interleukin-6, in combination with methotrexate in patients with rheumatoid arthritis inadequately controlled by tumour necrosis factor inhibitor therapy: efficacy and safety results of a randomised controlled phase III study
doi: 10.1007/s11033-025-10966-6

* **Niacinamide (Vitamin B3): An ingredient known for its ability to brighten the complexion, reduce the appearance of pores, regulate sebum production, and strengthen the skin's barrier

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