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Figure EV3 Mapping TDE0362 cleavage sites
Microglia recognize synOs through pattern recognition receptors such as Tolllike receptor (TLR)2, triggering activation of the NLRP3 inflammasome and a proinflammatory cascade [161]
[DOI] [PubMed] [Google Scholar] Moran JA, Dahl EL, et al
Soluble A binds to Fe3+ when extracellular iron increases, removing excess iron, but it is difficult to separate after interaction
This inhibitory effect escalated concomitantly with increasing drug loading
Therefore, Gln deprivation-induced iron death in tumor cells may represent a novel therapeutic strategy for liver tumors (47)
