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A promising therapeutic and preventive direction lies in the application of mitochondria-relevant nutraceuticals that help restore mitochondrial homeostasis, improve redox balance, and modulate inflammatory signalling

Front Med 12:518524

Liggett et al., 1992) (Fig

[1] [2] [3] [20] In order to prevent mitochondrial malfunction and sustain metabolic function/energy generation (ATP), NAD+ supplementation may counterbalance the age-related degradation of NAD+ and its precursor nicotinamide mononucleotide by NADases, particularly CD38

Transitional Approaches Some individuals find success with transitional protocols that begin at standard doses before tapering to micro-dose maintenance