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Mechanistic investigation revealed ChaC1/AUR-driven cytotoxicity was attenuated by disulfide reducing agents (e.g., NAC and TCEP), while maintaining resistance to canonical programmed death pathway inhibitors targeting apoptosis, necroptosis, and ferroptosis
The review emphasizes the importance of holistic approach of Ayurveda in using the Mucuna pruriens in treatment of PD
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Ferroptosis promotes neural cell death following SCI
