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The other form, 5-deoxyadenosylcobalamin, is a cofactor needed by the enzyme that converts L-methylmalonyl-CoA to succinyl-CoA

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Medication Interactions Certain medications reduce the absorption of methylcobalamin, cyanocobalamin, and other B12 supplements, including: Proton pump inhibitors (omeprazole, esomeprazole, and lansoprazole) H2-receptor antagonists (cimetidine, famotidine, and ranitidine) Metformin Colchicine Cholestyramine Certain antibiotics (neomycin and chloramphenicol) If you use these or other medications, talk with a healthcare provider about ways to maintain healthy levels of B12.

While Mounjaro acts on both GIP and GLP-1 receptors, Ozempic acts solely on GLP-1 receptors

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