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Dysregulation of SOCS-mediated negative feedback of cytokine signaling in carcinogenesis and its significance in cancer treatment

Its powerful antioxidant properties are believed to combat oxidative stress, which can lead to premature ageing and skin damage
doi: 10.5758/vsi.2014.30.4.113

J.BanerjeeA.SillimanC

10.1186/s13045-019-0720-y 35 MuttakinS.KimM

Although the cell death mechanism of RPE, which is susceptible to oxidative stress, remains controversial, ferroptosis has been recently recognized as a primary mode of RPE cell death (81)
