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Activation of this pathway stimulates both interferon regulatory factor3 (IRF3) and NFB activation and an array of downstream pro-inflammatory responses (Figure 2)

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Kawamatawong T (2021) Phosphodiesterase-4 inhibitors for non-COPD respiratory diseases

The NADPH organizers NoxO1 and p47phox are both mediators of diabetes-induced vascular dysfunction in mice
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