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Although there were no statistically significant differences between MOD and SEV groups regarding the occurrence of clinical complications, the outcomes were significantly worse for patients in the SEV group, with longer total hospitalization time ( P = 0.0132) and more frequent deaths ( P = 0.0036) ( Table 1 )

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On the other hand, a considerable although short-lasting increase in intraocular pressure may trigger or contribute to the major noxious process seen to progress with the L-NAME retrobulbar application and the supposed failure of NO-system adaptive capabilities [13]

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