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2 - Synuclein as the chief mediator of synucleinopathies Parkinsons disease (PD) is the second most abundant neurological disease after Alzheimer which primarily affects co-ordination in movement

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Curcuminoids, olive-associated polyphenols (including secoiridoids and 5-HT), coumarins, and flavonolignans As explained before IBDs, represented by UC and CD, are two major inflammatory conditions potentially characterized by an abnormal mucosal immunological response associated with a heterogeneous phenotypic spectrum, triggered by gastrointestinal and extraintestinal affectations, or with atypical or non-specific symptoms [582]

Pharmacological PINK1 activation ameliorates Pathology in Parkinsons Disease models

In: Casas JS, Sordo J, eds

J Histochem Cytochem 62(1):7084