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Pavlikova, N., Kortner, T

APOE4 moderates effects of cortical iron on synchronized default mode network activity in cognitively healthy old-aged adults

doi: 10.1111/jcpe.12063 [DOI] [PubMed] [Google Scholar] 12

This cascading event is exacerbated by aging with a declining proteostasis, thereby reducing the cells ability to protect its more vulnerable proteins from coaggregation, eventually resulting in the collapse of essential cellular functions
Vitamin B6 helps maintain healthy testosterone production by limiting oestrogen buildup that can work against testosterone's effects

The reality is more nuanced
