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Insurmountable landscape features, such as mountains and rivers, typically drive such processes, and in cases where genetic differentiation persists even after dispersal between formerly isolated populations could resume, such entities can then be designated as separate species (Figure 3)

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Impaired activity of the ubiquitinproteasome system in transgenic mice expressing ALS/dementia-linked mutant UBQLN2 (P02.170) Neurology

Available from: [DOI] [PMC free article] [PubMed] [Google Scholar] 163.Zhang F, Lv M, Wang S, Li M, Wang Y, Hu C, et al

Age As individuals age, their ability to absorb vitamin B12 diminishes, primarily due to decreased production of stomach acid or intrinsic factor, a protein necessary for B12 absorption

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