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doi: 10.1016/j.jconrel.2017.01.032, 166

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E N D Presentation Transcript L-Carnitine Charisma Garcia NFSC 345 Introduction Background Purported Benefits Mechanism of Action Evidence of Benefits Conflicting Research Safety Concerns Professional Position L-Carnitine Essential for Energy Production Naturally Occurs in the Human Body Synthesized in the Liver & Kidneys Derived from the amino acid, Lysine Produces 11-34mg/day (Sufficient to meet all needs!) Dietary L-Carnitine Red meat, dairy, fish, wheat, asparagus, avocado Omnivorous diet: 20-200mg/day (~75% absorbed) No proof of Dietary need exists L-Carnitine as a Supplement Liquid form,Tablets & Capsules Typical Dose: 1000-6000 mg/day ~20% absorbed by the body Generally non-toxic Intended population: Athletes Dieters Purported Benefits Primary Systemic Carnitine Deficiency A recessive gene mutation Cardiovascular Disease Alzheimers Disease Chronic Fatigue In the Elderly Population In Cancer Patients Fat Loss No Evidence EXERCISE PERFORMANCE

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Shibata N, Kunisawa J, Hosomi K et al (2018) Lymphoid tissue-resident Alcaligenes LPS induces IgA production without excessive inflammatory responses via weak TLR4 agonist activity