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Description
Chaperones attempt to remedy the unfolded protein first and, if unsuccessful, activate cellular programs, including the UPR, heat shock response (HSR), and ER-associated degradation (ERAD), to induce processes to either fix the problem or destroy the unfolded proteins (324, 325)

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Study Selection The identified articles were analyzed in three stepstitle, abstract, and full text

53 Tubular epithelial cells are particularly susceptible to glucose-induced metabolic derangements

Med Oncol

Prognostic implications of magnetic resonance-derived quantification in asymptomatic patients with organic mitral regurgitation: comparison with Doppler echocardiography-derived integrative approach