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Acute COVID-19 is characterized by a significant dysregulation of molecules that may lead to endothelial disruption, platelet hyperactivation, microthrombosis, and compromised microcirculation [333,334,335]

LRG1 promotes apoptosis and autophagy through the TGF-smad1/5 signaling pathway to exacerbate ischemia/reperfusion injury
[DOI] [PMC free article] [PubMed] [Google Scholar] [224].Turner E, Hager LJ, Shapiro BM, Ovothiol replaces glutathione peroxidase as a hydrogen peroxide scavenger in sea urchin eggs, Science 242 (4880) (1988) 939941