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The liver maintains the highest concentrations, reflecting glutathione's central role in detoxification processes

doi: 10.1016/j.intimp.2017.02.017 120 HuangGWangYChiH

doi: 10.3389/fimmu.2015.00227, PMID: 20 DeyPKimmelmanACDePinhoRA

Microbiome modulation: Probiotics, prebiotics, and postbiotics in Acne vulgaris therapy

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Extracellular signal-regulated protein kinases (ERK) [24], c-jun N -terminal kinase (JNK) [24], PI3K-AKT [19], protein kinase C (PKC) [25], casein kinase 2 (CK2) [26], and protein kinase R (PKR)-like endoplasmic reticulum kinase (PERK) [27] were reported to mediate phosphorylation of NRF2 and increase its stability and subsequent transcriptional activity, whereas p38 and GSK3-mediated phosphorylation of NRF2 decreases NRF2 stability [19]