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Dysfunction within the CNS Brain imaging studies have demonstrated an association between PDPN and structural changes in key somatosensory regions, such as the thalamus and somatosensory cortex, and altered functional connectivity within ascending pain pathways and cortical regions involved in pain processing

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It is a limitation of the study that the midbrain organoid sets were generated from iPSCs from only one healthy donor and one PD patient

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Is 10 mg a safe weekly dose of retatrutide