alex kikel l carnitine Kikel: Peptides, Mitochondria, and the Future of Longevity #421 The Complete Guide to Exogenous

Gene expression data for ABCC1 were extracted from the Haferlach Leukemia, Valk Leukemia or TCGA Leukemia datasets (reporter: 202804_at) using the Oncomine Research Premium Edition database (Thermo Fisher, USA) 88 , accessed in July, 2021

Furthermore, investigating the relative degree of tumor dependency on exogenous glutamine at distinct stages of tumorigenesisthat is, in the primary tumor initiation and expansion, local tissue invasion, survival in the circulation and seeding, and colonization of distant organsmay provide further insights into the therapeutic potential of targeting glutamine metabolism in cancer therapy

doi: 10.1183/13993003.02559-2020

PubMed CrossRef Sproule BA, Hazra M, Pollock BG

This includes mitochondrial dysfunction and metabolic and oxidative stress

It is not only closely linked to the systemic complications of diabetes but also involves specific pathological changes in myocardial metabolism and oxidative stress (1)